CYBERNETICS INSANE 250gr

Pre-workout product for Nitric Oxide production

Nitric oxide supplements are designed to enhance workout performance by increasing energy, endurance, and focus. Below are the key benefits of each ingredient in CYBERNETICS INSANE, supported by scientific studies:

1. Bitter Orange Peel Extract: Energy and Metabolism Boost

Bitter orange contains synephrine, which boosts metabolism and energy levels.
• Study: Ruiz-Moreno, C., Del Coso, J., Giráldez-Costas, V., González-García, J., & Gutiérrez-Hellín, J. (2021). Effects of p-Synephrine during Exercise: A Brief Narrative Review. Nutrients, 13(1), 233.
• Result: Bitter orange, especially its synephrine content, has been shown to increase energy expenditure, support fat burning, and enhance physical performance.

2. Rhodiola Rosea Extract: Reduces Fatigue and Improves Focus

Rhodiola Rosea is an ingredient that reduces stress and enhances both physical and mental endurance.
• Study: Tinsley, G. M., Jagim, A. R., Potter, G. D. M., Garner, D., & Galpin, A. J. (2024). Rhodiola rosea as an adaptogen to enhance exercise performance: a review of the literature. The British Journal of Nutrition, 131(3), 461–473.
• Study: Parisi, A., Tranchita, E., Duranti, G., Ciminelli, E., Quaranta, F., Ceci, R., Cerulli, C., Borrione, P., & Sabatini, S. (2010). Effects of chronic Rhodiola Rosea supplementation on sport performance and antioxidant capacity in trained males: preliminary results. The Journal of Sports Medicine and Physical Fitness, 50(1), 57–63.
• Result: Rhodiola Rosea has been found to enhance physical and mental performance by reducing fatigue and improving endurance.

3. N-Acetyl-L-Tyrosine and DMAE-Bitartrate: Support for Cognitive Functions

N-Acetyl-L-Tyrosine helps in the production of neurotransmitters that improve alertness and focus. DMAE-Bitartrate enhances memory and cognitive functions.
• Study: Bloemendaal, M., Froböse, M. I., Wegman, J., Zandbelt, B. B., van de Rest, O., Cools, R., & Aarts, E. (2018). Neuro-Cognitive Effects of Acute Tyrosine Administration on Reactive and Proactive Response Inhibition in Healthy Older Adults. eNeuro, 5(2), ENEURO.0035-17.2018.
• Result: Tyrosine improves cognitive function, particularly in situations that require mental performance under stress.
• Study: Dimpfel, W., Wedekind, W., & Keplinger, I. (2003). Efficacy of dimethylaminoethanol (DMAE) containing vitamin-mineral drug combination on EEG patterns in the presence of different emotional states. European Journal of Medical Research, 8(5), 183–191.
• Result: DMAE is recommended for supporting cognitive function and enhancing memory.

4. Caffeine: Energy and Fatigue Reduction

Caffeine increases energy, focus, and reduces fatigue.
• Study: Spriet, L. L. (1995). Caffeine and performance. Journal of Applied Physiology, 79(3), 937-949.
• Result: Caffeine has shown significant improvement in endurance performance by reducing fatigue and increasing energy levels.

5. Glucuronolactone and Taurine: Endurance and Recovery

Glucuronolactone helps reduce fatigue and remove toxins. Taurine supports hydration and has antioxidant properties.
• Study: Munteanu, C., & Schwartz, B. (2023). B Vitamins, Glucoronolactone and the Immune System: Bioavailability, Doses and Efficiency. Nutrients, 16(1), 24.
• Result: Both taurine and glucuronolactone are safe as supplements, with taurine providing antioxidant benefits and enhancing hydration, while glucuronolactone helps reduce fatigue.

6. Beta-Alanine: Delays Fatigue and Improves Endurance

Beta-alanine increases carnosine levels, reducing lactic acid buildup during exercise.
• Study: H Cimadevilla-Fernández-Pola, E., Martínez-Roldán, C., Maté-Muñoz, J. L., Guodemar-Pérez, J., Sánchez-Calabuig, M. A., García-Fernández, P., Hervás-Pérez, J. P., & Hernández-Lougedo, J. (2024). Effects of β-Alanine Supplementation on Subjects Performing High-Intensity Functional Training. Nutrients, 16(14), 2340.
• Study: Harris, R. C., & Sale, C. (2012). Beta-alanine supplementation in high-intensity exercise. Medicine and Sport Science, 59, 1–17.
• Result: Beta-alanine increases carnosine content in muscles, which delays the onset of fatigue during high-intensity exercise.

7. Vitamins C, Niacin, B6, and Pantothenic Acid: Support for Energy and Recovery

Vitamin C provides protection from oxidative stress, reducing muscle fatigue. Niacin and pantothenic acid help with energy metabolism. Vitamin B6 aids in protein synthesis and maintaining energy levels.
• Study: Theodosis-Nobelos, P., & Rekka, E. A. (2024). The Antioxidant Potential of Vitamins and Their Implication in Metabolic Abnormalities. Nutrients, 16(16), 2740.
• Study: Tardy, A. L., Pouteau, E., Marquez, D., Yilmaz, C., & Scholey, A. (2020). Vitamins and Minerals for Energy, Fatigue, and Cognition: A Narrative Review of the Biochemical and Clinical Evidence. Nutrients, 12(1), 228.
• Study: Kennedy D. O. (2016). B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review. Nutrients, 8(2), 68.
• Study: Hrubša, M., Siatka, T., Nejmanová, I., Vopršalová, M., Kujovská Krčmová, L., Matoušová, K., Javorská, L., Macáková, K., Mercolini, L., Remião, F., Máťuš, M., Mladěnka, P., & On Behalf Of The Oemonom (2022). Biological Properties of Vitamins of the B-Complex, Part 1: Vitamins B1, B2, B3, and B5. Nutrients, 14(3), 484.